Pregnancy and Immunization
If you are pregnant, make sure you tell your healthcare professionals before you are immunized against anything. In general, pregnant women may be immunized with vaccines made from bacterial or viral noninfectious fragments, such as proteins, polysaccharides, or toxins. They may also receive vaccines made from inactive whole bacteria or viruses. However, some experts recommend against the use of immunizing agents during the first trimester to avoid febrile reactions. "Live" vaccines (such as for measles and chickenpox) are contraindicated due to the theoretical risk of transmitting the infection to the fetus. Reassuringly, as of yet, no vaccine (live, inactive or other) has been associated with congenital anomalies.
The following table presents a summary of major infections, and specific recommendations regarding the application of their vaccines during pregnancy:
| INFECTION | RECOMMENDATION |
| Chicken pox | *** Vaccine contraindicated *** |
| Cholera | Undetermined safety; should accept vaccine only in high-risk situations. |
| Hepatitis-A | Immunoglobulins considered safe; can accept if indicated.Vaccine undetermined safety; accept only in high-risk situation |
| Hepatitis-B | Can accept both immunoglobulins and vaccine if indicated. |
| Influenza | Can accept vaccine if indicated |
| Japanese encephalitis | Undetermined safety; accept vaccine only in high-risk situations. |
| Lyme Disease | *** Vaccine contraindicated *** |
| Measles, Mumps, Rubella (German measles) | *** Vaccine contraindicated *** |
| Meningococcus | Undetermined safety; should accept vaccine only in high-risk situations. |
| Plague | Undetermined safety; should accept vaccine only in high-risk situations. |
| Pneumococcus | Can accept if indicated. |
| Polio | Can accept (killed virus) vaccine if indicated but preferably only after the first trimester. |
| Rabies | Can accept both immunoglobulins and vaccine if indicated. |
| Tetanus | Can accept immunoglobulins against tetanus if indicated; if dose required routinely, only accept after first trimester. Can accept vaccine (tetanus-diptheria) if indicated |
| Tuberculosis | Should accept BCG (Bacillus Calmette-Guerin) vaccine only in high-risk situations. |
| Typhoid | Undetermined safety; accept vaccine only in high-risk situations. |
| Yellow fever | Undetermined safety; should accept vaccine only in high-risk situations and preferably only after the first trimester. |
For more information:
The Canadian Coalition for Immunization Awareness & Promotion
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The patient information leaflets are provided by Vigilance Santé Inc. This content is for information purposes only and does not in any manner whatsoever replace the opinion or advice of your health care professional. Always consult a health care professional before making a decision about your medication or treatment.